DRESS Syndrome
Medical Research and Papers

Patient-Specific Resources

​

• JAMA Dermatology Patient Page: DRESS Syndrome 

​

• NORD (National Organization for Rare Diseases) DReSS Syndrome 

 

>> back to list

 

DRESS Syndrome Diagnosis and Management

 

2024

 

Newest Published International Consensus Guidelines

 

• Management of Adult Patients With Drug Reaction With Eosinophilia and Systemic Symptoms

        A Delphi-Based International Consensus

​

• International expert panel publishes guidelines for management of DRESS (from HHV-6 Foundation) open access

​

Two-Part Consensus Paper on Diagnostics and Management of DRESS

​

• Part 1: Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Epidemiology, pathogenesis, clinicopathological features, and prognosis

​​

• Part 2: Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Diagnosis and management

​​

Recently Published Comprehensive DRESS Paper in New England Journal of Medicine (NEJM)

 

• Drug Reaction with Eosinophilia and Systemic Symptoms  (Kroshinsky, Cardones, Blumenthal)

​

2023–2024

​

• DRESS syndrome: A literature review and treatment algorithm open access

​​

• Treatment of prolonged drug reaction with eosinophilia and systemic symptoms syndrome with dupilumab using a molecularly-guided approach: A case report open access

​​

• First-line therapy in drug reaction with eosinophilia and systemic symptoms (DReSS): Thinking beyond corticosteroids open access

​

2022

​

• Drug-Induced Hypersensitivity Syndrome (DIHS)/ Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): Clinical Features and Pathogenesis

​

• Drug Allergy Practice Parameter Updates to Incorporate Into Your Clinical Practice open access

​​

• Drug allergy: A 2022 practice parameter update

​

2021

​

• Updates and Insights in the Diagnosis and Management of DRESS Syndrome open access

​

2020

​

• Spanish Guidelines for Diagnosis, Management, Treatment, and Prevention of DRESS Syndrome open access

>> back to list

​

Emergency Medicine and DRESS

​​

2022

​

• Drug reaction with eosinophilia and systemic symptoms: An emergency medicine focused review

​​

2017

​

• DRESS Emergency Medicine Artricle by Dr. Susan Burgin open access

​>> back to list

 

​Genetic (HLA) Association With DRESS–Inducing Drugs

​​

2023

​

• Drug reaction eosinophilia and systemic symptoms: Clinical phenotypic patterns according to causative drug 

​​

2022

​

• Drug-Induced Hypersensitivity Syndrome (DIHS)/ Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): Clinical Features and Pathogenesis

​

• Practical implementation of genetics: new concepts in immunogenomics to predict, prevent and diagnose drug hypersensitivity

​​

• A low-cost, sensitive and specific PCR-based tool for rapid clinical detection of HLA-B*35 alleles associated with delayed drug hypersensitivity reactions

​

2021

​

• Immunopharmacogenomics: Mechanisms of HLA-Associated Drug Reaction open access​

​​

• HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms

 

• Risk Factors for Vancomycin Drug Reaction With Eosinophilia and Systemic Symptoms Syndrome

 

• Genomic Risk Factors Driving Immune-Mediated Delayed Drug Hypersensitivity Reactions open access

​>> back to list

​

​Viral Reactivation in DRESS

​

2024

​

• Latest Drug Hypersensitivity Articles from HHV-6 Foundation

​

2019

​

• The characteristics of patients with persistent HHV-6 infection after drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS)

​

2018

​

• HHV-6 encoded small non-coding RNAs define an intermediate and early stage in viral reactivation open access

>> back to list

 

DRESS Additional Key Papers

 

2021–2023

​

• Atypical Manifestations of DRESS Syndrome Without Eosinophilia. Case Report​​

​

• Current Perspective Regarding the Immunopathogenesis of Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms (DIHS/DRESS)  open access

​

• ​Drug-Induced Hypersensitivity Syndrome (DIHS)/ Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): Clinical Features and Pathogenesis open access

​​

2019

​

• Reporting of Drug Reaction with Eosinophilia and Systemic Symptoms from 2002–2019 in the FDA Adverse Event Reporting System (FAERS)  open access

​​

• Drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS): An update in 2019 open access

​

• Controversies in drug allergy: Testing for delayed reactions open access

​

2017–2018

​

• DRESS Syndrome: Clinical Myths and Pearls open access

​​

• Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): An Interplay among Drugs, Viruses, and Immune System open access

 

2013–2014

​

• DRESS syndrome – Descamps, Ranger-Rogez

​​

• DRESS Syndrome A Literature Review open access

​

​>> back to list

​

DRESS and Myocarditis (Heart Involvement)​

​

2023–2024

​

• Fatal Myocarditis in Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Without Mortality-Related Risk Factors: A Case Report and Literature Review open access

​

• DRESS Associated Myocarditis: Uncovering Hidden Medication Triggers open access

​​

• Predictors of mortality in DRESS-associated myocarditis: A systemiatic review

​

2020–2022

​

• “Heart in DRESS”: Cardiac Manifestations, Treatment and Outcome of Patients with Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome: A Systematic Review open access

​

• Myocarditis and Drug Rash With Eosinophilia and Systemic Symptoms Syndrome: A Deadly Combination open access

 

• A Novel Treatment for a Rare Cause of Cardiogenic Shock: DRESS open access

​

2017–2019

​

• WHEN YOUR HEART'S A MESS, THINK OF DRESS! open access

​​

• Myocarditis Associated with Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome: A Case Report and Review of the Literature open access

​​

• Refractory cardiac myocarditis associated with drug rash with eosinophilia and systemic symptoms syndrome due to anti-bipolar disorder drugs: a case report open access

​

• DRESS Syndrome Associated Eosinophilic Myocarditis Treated with Tofacitinib an oral Janus (JAK) Kinase Inhibitor

​

2012

​

• Minocycline-Induced Drug Reaction With Eosinophilia and Systemic Symptoms Syndrome: Myocarditis and Multiple Organ Failure - a case report open access

​​

>> back to list

​

DRESS in Skin of Color

2023​

​

• Recognizing Drug Hypersensitivity in Pigmented Skin open access

​

• Delayed diagnosis of DRESS syndrome in a patient with skin of color open access

​

​

>> back to list​​

​​​

Pediatric DRESS

​​​

2023–2024

​

• Pediatric drug reaction with eosinophilia and systemic symptoms: A 12-year retrospective study in a tertiary center

​

• Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in childhood: a narrative review open access

​

• Management and Long-Term Outcomes of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) in Children: A Scoping Review

>> back to list

​

Psychological Effects of DRESS

​​

2024

​

• Understanding the Patient Experience of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): A Qualitative Study

​​

2015 ​

​

• Post‐traumatic stress disorder following drug reaction with eosinophilia and systemic symptoms

>> back to list