DRESS Syndrome
Medical Research and Papers

Patient-Specific Resources

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• JAMA Dermatology Patient Page: DRESS Syndrome 

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• NORD (National Organization for Rare Diseases) DReSS Syndrome 

 

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DRESS Syndrome Diagnosis and Management

 

2024

 

Newest Published International Consensus Guidelines

 

• Management of Adult Patients With Drug Reaction With Eosinophilia and Systemic Symptoms

A Delphi-Based International Consensus

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• International expert panel publishes guidelines for management of DRESS (from HHV-6 Foundation) open access

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Recently Published Two-Part Paper on Diagnostics and Management

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• Part 1: Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Epidemiology, pathogenesis, clinicopathological features, and prognosis

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• Part 2: Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Diagnosis and management

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2023–2024

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• DRESS syndrome: A literature review and treatment algorithm open access

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• Treatment of prolonged drug reaction with eosinophilia and systemic symptoms syndrome with dupilumab using a molecularly-guided approach: A case report open access

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• First-line therapy in drug reaction with eosinophilia and systemic symptoms (DReSS): Thinking beyond corticosteroids open access

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2022

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• Drug-Induced Hypersensitivity Syndrome (DIHS)/ Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): Clinical Features and Pathogenesis

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• Drug Allergy Practice Parameter Updates to Incorporate Into Your Clinical Practice open access

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• Drug allergy: A 2022 practice parameter update

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2021

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• Updates and Insights in the Diagnosis and Management of DRESS Syndrome open access

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2020

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• Spanish Guidelines for Diagnosis, Management, Treatment, and Prevention of DRESS Syndrome open access

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Emergency Medicine and DRESS

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2022

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• Drug reaction with eosinophilia and systemic symptoms: An emergency medicine focused review

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2017

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• DRESS Emergency Medicine Artricle by Dr. Susan Burgin open access

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​Genetic (HLA) Association With DRESS–Inducing Drugs

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2023

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• Drug reaction eosinophilia and systemic symptoms: Clinical phenotypic patterns according to causative drug 

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2022

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• Drug-Induced Hypersensitivity Syndrome (DIHS)/ Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): Clinical Features and Pathogenesis

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• Practical implementation of genetics: new concepts in immunogenomics to predict, prevent and diagnose drug hypersensitivity

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• A low-cost, sensitive and specific PCR-based tool for rapid clinical detection of HLA-B*35 alleles associated with delayed drug hypersensitivity reactions

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2021

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• Immunopharmacogenomics: Mechanisms of HLA-Associated Drug Reaction open access​

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• HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms

 

• Risk Factors for Vancomycin Drug Reaction With Eosinophilia and Systemic Symptoms Syndrome

 

• Genomic Risk Factors Driving Immune-Mediated Delayed Drug Hypersensitivity Reactions open access

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​Viral Reactivation in DRESS

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2024

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• Latest Drug Hypersensitivity Articles from HHV-6 Foundation

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2019

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• The characteristics of patients with persistent HHV-6 infection after drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS)

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2018

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• HHV-6 encoded small non-coding RNAs define an intermediate and early stage in viral reactivation open access

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DRESS Key Papers

 

2021–2023

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• Atypical Manifestations of DRESS Syndrome Without Eosinophilia. Case Report​​

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• Current Perspective Regarding the Immunopathogenesis of Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms (DIHS/DRESS)  open access

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• ​Drug-Induced Hypersensitivity Syndrome (DIHS)/ Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS): Clinical Features and Pathogenesis open access

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2019

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• Reporting of Drug Reaction with Eosinophilia and Systemic Symptoms from 2002–2019 in the FDA Adverse Event Reporting System (FAERS)  open access

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• Drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS): An update in 2019 open access

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• Controversies in drug allergy: Testing for delayed reactions open access

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2017–2018

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• DRESS Syndrome: Clinical Myths and Pearls open access

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• Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): An Interplay among Drugs, Viruses, and Immune System open access

 

2013–2014

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• DRESS syndrome – Descamps, Ranger-Rogez

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• DRESS Syndrome A Literature Review open access

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DRESS and Myocarditis (Heart Involvement)​

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2023–2024

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• Fatal Myocarditis in Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Without Mortality-Related Risk Factors: A Case Report and Literature Review open access

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• DRESS Associated Myocarditis: Uncovering Hidden Medication Triggers open access

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• Predictors of mortality in DRESS-associated myocarditis: A systemiatic review

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2020–2022

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• “Heart in DRESS”: Cardiac Manifestations, Treatment and Outcome of Patients with Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome: A Systematic Review open access

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• Myocarditis and Drug Rash With Eosinophilia and Systemic Symptoms Syndrome: A Deadly Combination open access

 

• A Novel Treatment for a Rare Cause of Cardiogenic Shock: DRESS open access

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2017–2019

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• WHEN YOUR HEART'S A MESS, THINK OF DRESS! open access

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• Myocarditis Associated with Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome: A Case Report and Review of the Literature open access

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• Refractory cardiac myocarditis associated with drug rash with eosinophilia and systemic symptoms syndrome due to anti-bipolar disorder drugs: a case report open access

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• DRESS Syndrome Associated Eosinophilic Myocarditis Treated with Tofacitinib an oral Janus (JAK) Kinase Inhibitor

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2012

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• Minocycline-Induced Drug Reaction With Eosinophilia and Systemic Symptoms Syndrome: Myocarditis and Multiple Organ Failure - a case report open access

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DRESS in Skin of Color

2023​

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• Recognizing Drug Hypersensitivity in Pigmented Skin open access

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• Delayed diagnosis of DRESS syndrome in a patient with skin of color open access

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Pediatric DRESS

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2023–2024

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• Pediatric drug reaction with eosinophilia and systemic symptoms: A 12-year retrospective study in a tertiary center

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• Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in childhood: a narrative review open access

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• Management and Long-Term Outcomes of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) in Children: A Scoping Review

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Psychological Effects of DRESS

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2024

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• Understanding the Patient Experience of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): A Qualitative Study

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2015 ​

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• Post‐traumatic stress disorder following drug reaction with eosinophilia and systemic symptoms

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